TROPHOBLASTIC GIANT CELL TRANSFORMATION OF MOUSE BLASTOCYSTS
نویسندگان
چکیده
منابع مشابه
Induction of the trophoblastic giant-cell transformation after ovariectomy in the mouse.
INTRODUCTION The trophoblastic giant-cell transformation of mouse blastocysts (Duval, 1891; Dickson, 1963) is blocked by ovariectomy carried out on the fourth day of gestation (Dickson, 19666)Such blocked blastocysts have a greater overall length and a shorter inner cell mass, and hence a larger blastocoele, thanuntransformed blastocysts from mice that have not been ovariectomized (Dickson, 196...
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Trophoblastic tissues grown under different conditions in vitro display distinct patterns of cellular growth. Thus, trophoblast cultured on 'bacteriological grade' plastic surfaces remained in suspension culture as rounded tissue fragments. Such tissues maintained numerous cell contacts and remained, in turn, largely diploid. Trophoblast explanted on a 'tissue-culture grade' substrate formed mo...
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The malignant transformation of conventional giant cell tumor of bone (GCTOB) is rare and usually occurs with irradiation. Here we report two neglected cases of conventional GCTOB with spontaneous malignant transformation at 11 and 16 years after initial diagnosis. In the former case, the patient refused to receive any treatment following the incisional biopsy, and in the latter, the firs...
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Preimplantation mouse blastocysts were dissected into inner cell mass (ICM) and trophoblast cells. These fragments were transferred to pseudo-pregnant mice which were left intact or ovariectomized. The latter group received progesterone to permit blastocysts and the dissected fragments to enter into quiescence, prior to injection of oestradiol to induce implantation. Trophoblastic vesicles, wit...
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1. Inner cell mass (ICM) and trophoblast tissue were isolated from 3^-day post-coitum mouse blastocysts that were homozygous for different electrophoretic variants of the enzyme glucose phosphate isomerase (GPI). Blastocysts were reconstituted from these tissues, transferred to pseudo-pregnant recipients and allowed to develop to the early somite stage. 2. The embryo plus membranes and trophobl...
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ژورنال
عنوان ژورنال: Reproduction
سال: 1963
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0060465